REST Protein May Play Protective Role Against Alzheimer's and Other Dementias

Bruce Yankner, M.D., Ph.D., led a recent study (not funded by Cure Alzheimer's Fund) on a protein called REST. His results suggest that this protein may protect neurons from damage such as oxidative stress and inflammation. The study also gives us clues as to why plaques and tangles, two well-known features of Alzheimer's pathology, may not always cause cognitive decline.

Art and Alzheimer's: Tim Armour on WGBH

In recent years, depictions of dementia on the stage and screen have become increasingly common. On February 20, 2014, Cure Alzheimer's Fund president and CEO Tim Armour appeared on WGBH News to discuss art and Alzheimer's disease. He was joined by WGBH arts editor Jared Bowen to talk about a recent play, "Absence", which tells the story of a woman living with dementia through her own eyes.

Dementia Costs On Par with Cancer and Heart Disease

According to a new RAND study published today in the New England Journal of Medicine, dementia care costs are now comparable to those of heart disease and cancer. And unlike most chronic diseases, rates of dementia in the population are rising rapidly. The study estimates that about 3.8 million Americans currently suffer from dementia, and predicts that this number will climb to 9.1 million by 2040. The cost of the disease to the country will rise proportionally if a cure is not found.

New Report: 35 million suffer from dementia worldwide - projected to reach 115 million by 2050

Today is World Alzheimer's Day, and the big news of the day is a report from Alzheimer's Disease International, which paints a grim picture of the future if this devastating disease goes unchecked. The report says that currently 35 million people worldwide suffer from Alzheimer's Disease - and that number is expected to double every twenty years, reaching 115 MILLION Alzheimer's and dementia sufferers by 2050.

Here's an excerpt from the report:

Not only are the numbers reason for concern, but Alzheimer's disease and dementia have an enormous impact on societies; it can be called an epidemic that is increasing its pace with the "graying" of the population around the world. Poor recognition, underdiagnosis and stigma cause significant problems for people with dementia and their families in countries of all sizes and communities of all income levels.

The ADI report also highlights the financial costs of dementia, which were estimated to be over $300 billion in 2005 alone. These costs, currently borne mostly in the developed world, are also expected to skyrocket together with global rates of the disease. Already, the costs of caring for Alzheimerís and dementia patients consume over one quarter of the US Medicare and Medicaid budgets. If left unchecked, Cure Alzheimer's Fund's estimates suggest they could single-handedly bankrupt Medicare and Medicaid within the next decade.

We are dedicated to ensuring that this grim picture does not come to pass. We've made tremendous progress already, and we are working to find a cure by 2020. But to get there, we need your continued support. Please donate to help us find a cure and stop this devastating disease.