What do the developing brain and the Alzheimer’s brain have in common? Beth Stevens, Ph.D., a developmental neurologist, is investigating an important connection: the loss of synapses, where neurons connect with one another to transmit important signals.
Find out about the exciting progress being made with gamma secretase modulators, a potential drug therapy for Alzheimer’s, in this one-hour webinar. Steven Wagner, Ph.D., principal investigator at UC San Diego's Department of Neuroscience, talks to David Shenk, senior adviser, Cure Alzheimer's Fund, about how the modulators work and what’s being done to get them to human trials. This webinar was recorded at our annual Research Consortium meeting in San Diego.
Last week, many news stories broke about a recent study suggesting levels of amyloid, the sticky substance that builds up in the brain of Alzheimer's patients, may be lowered by the antidepressant Celexa. Dr. Rudy Tanzi, of Harvard Medical School/Massachusetts General Hospital and chair of Cure Alzheimer's Fund's Research Consortium, appeared on the CBS Morning Show to discuss the story.
Five new publications by Gal Bitan, Ph.D., and colleagues of the David Geffen School of Medicine at UCLA have been released on developing the "molecular tweezer"* CLR01 as a therapeutic drug for Alzheimer's disease and other amyloidoses (conditions involving the build-up of insoluble amyloid proteins).
Dr. Rudy Tanzi of Harvard Medical School/Mass General Hospital talks to David Shenk about his research into CD33 inhibitors, which show promise in curtailing the damaging brain inflammation that occurs in Alzheimer's disease.