Getting to a Cure
Why do we need a National Strategy?
- The cost of care for Alzheimer’s patients will overwhelm Medicare and Medicaid if not checked within the next few years.
- With funding from private and public sources heavily constrained, it is essential to make each research dollar count. There is enough consensus in the AD research community now to posit a direction for further research that will maximize resources and minimize the time to a cure.
Cure Alzheimer's Fund proposes a National Research Strategy to accelerate progress toward a cure. The proposal builds on our own Research Roadmap, and provides a broader path to intervention by 2020.
We have shared this draft with selected members of Congress and their staffs, and with the staff of the Alzheimer's Study Group , a bipartisan effort co-chaired by Newt Gingrich and former Senator Bob Kerrey, and featuring others including Justice Sandra Day O’Connor, Harold Varmus and our own Henry McCance. It is our goal to work collectively with other funding organizations, the National Institutes of Health and related government agencies to avert the looming crisis of Alzheimer’s. If we can agree on the fundamentals of a national research strategy, we can save millions of lives and billions of dollars within the next decade.
Cure Alzheimer's Fund's National Research Strategy>
Q&A on National Research Strategy>
Dr. Sisodia of the University of Chicago and Dr. Gabe of the University of California at Irvine have been awarded the prestigious distinction of fellow of the American Association for the Advancement of Science (AAAS). Founded in 1848, AAAS is the world’s largest general scientific society and publisher of the journal Science.
Dr. Sisodia, a member of the Cure Alzheimer's Fund Research Consortium, is being recognized “for extraordinary contributions to understanding the function and dysfunction of APP and Presenilin 1 in cellular and animal models of Abeta amyloidosis in Alzheimer’s disease.”
Read more in the University of Chicago Chronicle
Dr. Glabe is also a member of the Cure Alzheimer’ Fund Research Consortium and a Professor of Molecular Biology & Biochemistry School of Biological Sciences at UC Irvine. He was one of 20 UC Irvine science and engineering researchers named as AAAS fellows, the largest class in 2008 of any university or institution in the United States.
Alzheimer's Charity Finds Success in Stuart, FL. A recent TC Palm article features the breakthrough work of the Alzheimer's Genome Project and describes the origin of Cure Alzheimer's Fund.
By BY JAN LINDSEY Correspondent
Wednesday, December 24, 2008
STUART — Philanthropist Phyllis Rappaport, a Stuart resident, knows how to pick 'em. The Rappaports were one of four families to found the Cure Alzheimer's Fund in 2004, primarily to back the work of Rudy Tanzi, a scientist affiliated with Harvard University and Massachusetts General Hospital. This year, Tanzi identified 40 human genes related to Alzheimer's and made Time magazine's list of the Top 10 Medical Breakthroughs of 2008.
Boston Globe story focuses on Cure Alzheimer's Fund study that shows mice given an anesthetic widely used in surgery on people suffered changes to their brains similar to the damage found in Alzheimer's disease. The results by researchers from Dr. Rudy Tanzi of Massachusetts General Hospital was published in the online Annals of Neurology. The results need to be tested in humans, the authors caution, but the findings raise questions about administering this kind of anesthesia to elderly patients with or without Alzheimer's.
Click here to read the full article
The first family-based genome-wide association study in Alzheimer’s disease has identified the sites of four novel genes that may significantly influence risk for the most common late-onset form of the devastating neurological disorder.
Four novel genes that may significantly increase the risk of the most common form of late-onset Alzheimer’s have been identified by researchers at Massachusetts General Hospital and Harvard Medical School, as reported in the November 7th issue of American Journal of Human Genetics. The findings, part of a larger “Alzheimer’s Genome Project” (AGP) established three years ago to identify the full set of Alzheimer’s disease genetic risk factors, may lead to more aggressive therapeutic interventions to slow, stop or even reverse the effects of the disease. These new therapies would differ from current treatments that only address the symptoms of the disease.
The award co-sponsored by the Cure Alzheimer's Fund and the Alzheimer's Association honors the legacies of two pioneering Alzheimer researchers, George G. Glenner and Leon J. Thal. The two $100,000 grants will be made to early career researchers to inspire and enable innovative research which leads to effective therapies for Alzheimer's Disease.
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