Alzheimer's Charity Finds Success in Stuart, FL. A recent TC Palm article features the breakthrough work of the Alzheimer's Genome Project and describes the origin of Cure Alzheimer's Fund.
By BY JAN LINDSEY Correspondent
Wednesday, December 24, 2008
STUART — Philanthropist Phyllis Rappaport, a Stuart resident, knows how to pick 'em. The Rappaports were one of four families to found the Cure Alzheimer's Fund in 2004, primarily to back the work of Rudy Tanzi, a scientist affiliated with Harvard University and Massachusetts General Hospital. This year, Tanzi identified 40 human genes related to Alzheimer's and made Time magazine's list of the Top 10 Medical Breakthroughs of 2008.
Boston Globe story focuses on Cure Alzheimer's Fund study that shows mice given an anesthetic widely used in surgery on people suffered changes to their brains similar to the damage found in Alzheimer's disease. The results by researchers from Dr. Rudy Tanzi of Massachusetts General Hospital was published in the online Annals of Neurology. The results need to be tested in humans, the authors caution, but the findings raise questions about administering this kind of anesthesia to elderly patients with or without Alzheimer's.
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The first family-based genome-wide association study in Alzheimer’s disease has identified the sites of four novel genes that may significantly influence risk for the most common late-onset form of the devastating neurological disorder.
Four novel genes that may significantly increase the risk of the most common form of late-onset Alzheimer’s have been identified by researchers at Massachusetts General Hospital and Harvard Medical School, as reported in the November 7th issue of American Journal of Human Genetics. The findings, part of a larger “Alzheimer’s Genome Project” (AGP) established three years ago to identify the full set of Alzheimer’s disease genetic risk factors, may lead to more aggressive therapeutic interventions to slow, stop or even reverse the effects of the disease. These new therapies would differ from current treatments that only address the symptoms of the disease.
The award co-sponsored by the Cure Alzheimer's Fund and the Alzheimer's Association honors the legacies of two pioneering Alzheimer researchers, George G. Glenner and Leon J. Thal. The two $100,000 grants will be made to early career researchers to inspire and enable innovative research which leads to effective therapies for Alzheimer's Disease.
Map of Alzheimer’s Genes May Lead to Novel Therapies
Dr. Rudolph Tanzi Speaks at International Conference on Alzheimer’s
Breakthrough genetic research to map all the genes connected to Alzheimer’s, which could lead to more aggressive treatment and a potential cure for the disease, was the focus of a presentation by leading Alzheimer’s researcher Dr. Rudolph Tanzi at the International Conference on Alzheimer’s Disease (ICAD) in Chicago.
It is rare to have an opportunity to combine a personal passion with something critical to the future of your family. Over the past year, I was fortunate to combine my passion for mountain climbing with a global effort to raise awareness and money for Alzheimer’s research.
No, Alzheimer’s is not a normal part of the aging process.
All parts of our bodies change as we age and this includes the brain. As people get older, they notice slowed thinking and changes in memory. However, the changes in memory associated with Alzheimer’s are not part of normal aging. Alzheimer’s disease is a progressive, irreversible and fatal brain disease.
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