A US News and World Report article profiles a new test to determine the effectiveness of Alzheimer's drugs developed by Cure Alzheimer's Fund's Dr. David Holtzman. The stable isotope-linked kinetics or SILK test quickly reveals whether medication is working to limit the harmful protein amyloid beta.
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The news media has been reporting dramatic drops in endowments and in funding for non-profits. How is Cure Alzheimer’s Fund doing?
Cure Alzheimer’s Fund has no endowment and we keep what funds are left after distribution to research and expenses in money market funds so we can have ready access to money to fund research. Therefore, we are not as exposed to quick changes in the market as many other non-profits are. We have not experienced the losses that so many non-profits are facing right now.
Leona M. and Harry B. Helmsley Charitable Trust announced today it has awarded a $300,000 grant to Cure Alzheimer’s Fund.
Annual Awards Support “Tomorrow’s Leaders in Alzheimer’s Disease Research;”
Honor Legacies of Drs. George Glenner and Leon Thal
April 9, 2008 – A coalition of leading Alzheimer’s disease organizations today announced the first three recipients of “Tomorrow’s Leaders in Alzheimer’s Disease Research” prizes; a new award mechanism to recognize outstanding young scientists in Alzheimer’s and dementia research.
Dr. Rob Moir
Researcher Dr. Rob Moir, a member of the Cure Alzheimer's Fund Oligomer Collaborative, and researcher at Massachusetts General Hospital in Boston, presented research supported by Cure Alzheimer's Fund in March to the International Conference on Alzheimer's Disease/Parkinson's Disease that points to evidence that the Abeta peptide, acknowledged to be implicated in the cause of AD, may in fact be a "part of our evolutionary ancient innate immune system." The work is a collaboration between Dr. Moir, Dr. Rudy Tanzi, Chair of the Cure Alzheimer's Fund Research Consortium, and infectious disease expert, Dr. James Kirby (Harvard Medical School).
Read the entire article by AlzForum's Gabrielle Strobel >
A paper released on April 1, 2009, in the Journal of Neuroscience corroborates Prana’s strategy to treat Alzheimer’s disease patients.
Says Dr. Charles Glabe, an author of the paper and member of Cure Alzheimer’s Fund Research Consortium, “these results are very exciting news for understanding the mechanism of Alzheimer’s pathogenesis. They help elucidate the fundamental role of metal ions like zinc in causing the formation of Abeta oligomers which damage synapses.”
While this paper did not have Cure Alzheimer’s Fund support, nor has Cure Alzheimer’s Fund supported the work of Prana, an Australian biotech company, the concepts involved have been central to investigations by Cure Alzheimer’s Fund’s Oligomer Collaborative, of which Dr. Glabe has been a part. (See the Oligomer Collaborative on our website. ) Please note that Dr. Rudy Tanzi, Chair of the Cure Alzheimer’s Fund Research Consortium, is a founder of Prana and endorses its pursuit of therapeutic interventions through anti-Abeta oligomer drugs such as Prana’s PBT2.
Independent Study Corroborates Prana's Strategy to Treat Alzheimer's Disease Patients>
Getting to a Cure
Why do we need a National Strategy?
- The cost of care for Alzheimer’s patients will overwhelm Medicare and Medicaid if not checked within the next few years.
- With funding from private and public sources heavily constrained, it is essential to make each research dollar count. There is enough consensus in the AD research community now to posit a direction for further research that will maximize resources and minimize the time to a cure.
The Alzheimer's Study Group was established on July 11, 2007 under the auspices of the Congressional Task Force on Alzheimer’s Disease with the charge of creating a National Alzheimer's Strategic Plan to overcome America’s mounting Alzheimer's crisis.
The National Alzheimer's Strategic Plan was released at a hearing before the U.S. Senate Special Committee on Aging on Wednesday, March 25th at 10:30 a.m. EDT.
The Alzheimer’s Study Group Strategic Plan>
Cure Alzheimer’s Fund recognizes the significant work of the Alzheimer’s Study Group and appreciates the solid framework they developed for a strategic national plan. However, we also believe we must be more aggressive and ambitious in defining a research agenda and timelines for development of effective therapies in our battle against this devastating disease. The last two decades have shown that understanding the causes and genetic risk factors for Alzheimer’s is absolutely critical to determining the disease models on which effective treatments and a potential cure should be based.
Cure Alzheimer’s Fund’s Statement on the Alzheimer’s Study Group’s Strategic Plan>
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