News

Find updates on the work of our researchers here, as well as news about recent advances in Alzheimer's science, funding and awareness.

Progress Toward a Cure?

We believe there is good progress being made toward an end to this terrible disease. But there’s more to finding a cure than meets the eye. In fact, there are 4 key steps on the road to a cure, and each one takes tremendous time, effort and money:

  • find all the genes that contribute to risk for the disease;
  • figure out which ones contribute the most and have the best prospects for treatment;
  • determine how these genes actually lead to increased risk;
  • and find the drug therapies that can most safely and effectively disrupt this link.

Progress along this path is accelerating. For instance, we now know, thanks to the Alzheimer’s Genome Project™ - supported by the Cure Alzheimer’s Fund - that there are more than 70 genes that contribute to risk for the disease. Some of these newly identified genes appear to be prime candidates for effective drug therapy.

Other recent discoveries have opened new doorways to understanding more about Alzheimer’s leading “bad guy”, the Abeta peptide. When these bind together and build up in the brain, they contribute to the dysfunction of critical neuronal synapses, disrupting the ability of cells in the brain to communicate with one another. We know more now about how those Abeta peptides come together and what might be done to keep them apart or clear them out of the brain before they do their damage.

Researchers know a lot more now than they did even five years ago. But it’s a life and death race. Today, about half of the population over 85 has the disease. The Baby Boomers are entering the prime age range at risk for Alzheimer’s (over 65), and as they continue to age we are facing an epidemic that could devastate families and ravage our economy.

So, how do we get to a cure quicker? We believe that by following the strategy outlined above and increasing funding for the most promising research, we will get there. We are making progress, but we still have a lot of work to do. Join us and help fund the cure in the next decade.

Welcome to the Cure Alzheimer’s Fund Blog

Starting today, this is your go-to spot to stay up to date on the cutting edge of Alzheimer’s research.

Our goal is to stop the disease for those who have it and ultimately prevent it from happening at all. So far, we’ve contributed 8.2 million dollars toward research and have identified more than 70 genes linked to the disease…and we’re not stopping until there’s an end to Alzheimer’s.

As we make progress toward a cure, we’re dedicated to keeping you informed about the latest advances and treatments.

Here are a few things you can expect to find on this blog:

  • Updates on the latest scientific advances in plain English – no PhD required!
  • Posts from our President and CEO Tim Armour about the projects the Cure Alzheimer’s community is helping to fund, like the Alzheimer’s Genome Project ™
  • Interviews and video posts from the research teams we support, giving you an inside look at where your donations go
  • News from our lead researcher, Dr. Rudy Tanzi, about the breakthroughs that are bringing us closer to a cure
  • Stories from families and caregivers, explaining why they’re joining in the fight for a cure

As we kick off this blog, we want to hear from you. Want more information about a specific project? Let us know. Think we’re using too much scientific jargon? Drop us a note. You can reach us at info@curealz.org

Research Consortium member David Holtzman featured in US News and World Report

A US News and World Report article profiles a new test to determine the effectiveness of Alzheimer's drugs developed by Cure Alzheimer's Fund's Dr. David Holtzman. The stable isotope-linked kinetics or SILK test quickly reveals whether medication is working to limit the harmful protein amyloid beta.

Click here to read full article

Rock Stars of Science Website goes Live

Rock stars and researchers, including Cure Alzheimer’s Fund’s Sam Gandy and Rudy Tanzi, shared the spotlight in the June GQ magazine. Now the related website is live with expanded interviews and photos. Learn more about the how scientists and rock stars are working together to accelerate cures for our most threatening diseases.

Rock Stars of Science website>
Page about Dr. Rudy Tanzi>
Page about Dr. Sam Gandy>

GQ Magazine to feature Cure Alzheimer's Fund's Tanzi and Gandy as "Rock Stars of Science"

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Photo credit: Ben Watts

Nationally recognized Cure Alzheimer’s Fund researchers Dr. Rudy Tanzi and Dr. Sam Gandy add another distinction to their scientific careers as they join rock celebrities Sheryl Crow, Josh Groban, hip hop artist and X-Men Origins: Wolverine co-star Will-i-am, Aerosmith’s Joe Perry; and Seal for a designer menswear photo shoot as a “Rock Star of Science” in the June issue of GQ Magazine, available nationally on May 25, 2009.

The Boston Globe wrote an editorial in support of the Geoffrey Beene/GQ "Rock Stars of Science" campaign.  Click here to read the editorial

Download the Full GQ Photo Feature>

Click here to see the profile on Dr. Tanzi on the "Rock Stars of Science" web site

Click here to see the profile on Dr. Gandy on the "Rock Stars of Science" web site

Q&A with President Tim Armour on Cure Alzheimer's Financial Position

The news media has been reporting dramatic drops in endowments and in funding for non-profits. How is Cure Alzheimer’s Fund doing?

Cure Alzheimer’s Fund has no endowment and we keep what funds are left after distribution to research and expenses in money market funds so we can have ready access to money to fund research. Therefore, we are not as exposed to quick changes in the market as many other non-profits are. We have not experienced the losses that so many non-profits are facing right now.

Cure Alzheimer's Fund's Tanzi & Gandy featured on ABCNews.com "On Call + Alzheimer's"

ABCNews.com has launched an online Alzheimer's disease resource featuring informative tips and facts to help people better understand this devastating disease. The site features videos of Alzheimer's experts and researchers answering questions about risk factors, research, latest treatments and other issues impacting people living with the disease and the people who care for them.

Cure Alzheimer's Fund's Dr. Rudy Tanzi and Dr. Sam Gandy are two of the experts highlighted on the web site. Videos of Tanzi and Gandy answering a series of questions about the disease can be found on the site under "Alzheimer's Questions" in the "Risk Factor & Prevention" and "Diagnosing Alzheimer's" areas.

Click here to see Dr. Tanzi answer "Are the genes for Alzheimer's known?

Click here to see Dr. Gandy answer "What is Alzheimer's Disease?"
Click here to visit the ABCNewsonline On + Alzheimer's web site

Helmsley Trust Awards $300,000 Grant to Cure Alzheimer's Fund

Leona M. and Harry B. Helmsley Charitable Trust announced today it has awarded a $300,000 grant to Cure Alzheimer’s Fund.

Three Winners of New Award for Younger Researchers Announced by Coalition of Alzheimer Organizations

Annual Awards Support “Tomorrow’s Leaders in Alzheimer’s Disease Research;”

Honor Legacies of Drs. George Glenner and Leon Thal

April 9, 2008 – A coalition of leading Alzheimer’s disease organizations today announced the first three recipients of “Tomorrow’s Leaders in Alzheimer’s Disease Research” prizes; a new award mechanism to recognize outstanding young scientists in Alzheimer’s and dementia research.

Amyloid beta protein may be a defense against Microbes!

Moir Photo
Dr. Rob Moir

Researcher Dr. Rob Moir, a member of the Cure Alzheimer's Fund Oligomer Collaborative, and researcher at Massachusetts General Hospital in Boston, presented research supported by Cure Alzheimer's Fund in March to the International Conference on Alzheimer's Disease/Parkinson's Disease that points to evidence that the Abeta peptide, acknowledged to be implicated in the cause of AD, may in fact be a "part of our evolutionary ancient innate immune system." The work is a collaboration between Dr. Moir, Dr. Rudy Tanzi, Chair of the Cure Alzheimer's Fund Research Consortium, and infectious disease expert, Dr. James Kirby (Harvard Medical School).

Read the entire article by AlzForum's Gabrielle Strobel >