Find updates on the work of our researchers here, as well as news about recent advances in Alzheimer's science, funding and awareness.

Off to the Coldest Spot on Earth!

After several years of planning, Alan Arnette is off to the first mountain of his 7 Summits Climb. His first climb is Mount Vinson in Antartica which is one of the coldest places on the planet (so maybe not the coldest spot on the earth!).

Follow his progress on his website>

Spry Living also just featured Alan, his campaign and efforts to raise money for a cure in a piece title Climbing for Alzheimer's and it's Caregivers>

Bon Voyage Alan and Happy Thanksgiving!

Ending Alzheimer's by 2020 - Podcast

Bob DeMarco is featuring a podcast entitled, Rudy Tanzi The Plan to End Alzheimer's by 2020, on his website, the Alzheimer's Reading Room. We encourage you to listen to the podcast, as Bob writes:

"Please listen to Dr. Tanzi's words carefully. You might want to listen more than once to get a good understanding of his approach, plan, and a clear understanding of why he is optimistic."

The Alzheimer's Reading Room is a terrific source of information for the entire Alzheimer's community. The blog focuses on those suffering from Alzheimer's disease, Alzheimer's caregivers, and the art of Alzheimer's caregiving.

To listen to the podcast on the Alzheimer's Reading Room site click here>



Did you miss Cure Alzheimer's Fund on NPR?

Take a moment for this excellent work reporting on our progress and explaining the important steps needed to get to a cure. Co-Founder and Chairman, Jeff Morby and Research Consortium Chair, Rudy Tanzi were also interviewed by Emily Rooney on Greater Boston and by Mindy Todd on The Point and featured in the Cape Cod Times.


Click here to listen to Parts One and Two of Venture Philanthropy: An Investors Approach to Curing Alzheimer's>


Watch the Greater Boston tv show>

Listen to The Point>

Read The Brain is their Business in the Cape Cod Times>


Climbing Mountains for a Cure

Alan Arnette was featured yesterday on Fox channel 43 announcing his 7 Summits Climb for Alzheimer's: Memories are Everything.

In this year-long challegne, Alan will attempt the highest summit on each continent. He's featured in this live clip explaining that he's taking on this challenge in honor and memory of his mother, Ida, who had AD and his desire to help eliminate this terrible disease. All funds raised will go to Cure Alzheimer's Fund.

Read more about Alan and this campaign ->

Support Alan's campaign for research>

Scaling Heights to Cure Alzheimer’s

Mountaineer to Raise Awareness and Research Funding for Alzheimer’s by Climbing the Highest Summit on the World’s Seven Continents


Boston, Mass – Embarking on a year-long challenge that he hopes will end at the top of the Carstensz Pyramid, mountain climber and Alzheimer’s disease advocate Alan Arnette will take on the greater challenge of raising money for research and public awareness of Alzheimer’s disease, the nation’s sixth most deadly disease.

“The mental and physical demands of scaling seemingly insurmountable peaks are not unlike the everyday challenges faced by those living with Alzheimer’s disease and their caregivers,” said Arnette, who cared for his mother with Alzheimer’s until her death last year. “Both involve understanding personal limitations, reaching out for support and taking steps daily on a very long road.”

All of the money Arnette raises on his year-long campaign - The 7 Summits Climb for Alzheimer’s: Memories are Everything - will go to Cure Alzheimer’s Fund™, a non-profit organization dedicated to raising money for targeted research with the highest probability of slowing, stopping or reversing Alzheimer’s disease.

The Alzheimer’s Immunotherapy Program of Janssen Alzheimer Immunotherapy and Pfizer Inc. is funding Arnette’s climbs. To support Arnette in raising funds for Cure Alzheimer’s Fund please visit

“Research is the key to solving the complexities of Alzheimer’s disease and Alan Arnette’s courageous fundraising efforts will help the Alzheimer’s community come one step closer to finding a cure,” said Tim Armour, President of the Cure Alzheimer’s Fund™.

“What are our life experiences and adventures about if not to create life-long memories that we can share and embellish, year after year, with friends and family? Memories are everything,” said Arnette, whose high-altitude climbs can be followed on and

An accomplished climber, Arnette retired from his job with a leading technology company to care for his mother, Ida, when she was diagnosed with Alzheimer’s. Since then, 54-year-old advocate has worked to raise money for this disease that has no known cure. With The 7 Summits Climb for Alzheimer’s, he hopes to raise awareness of the impact of the disease and is also striving to raise $1 million for research.

Arnette departs on the first of his seven climbs on November 24, 2010. The first peak is the 16,067-foot (4897 meter) Mt. Vinson Massif in Antarctica. By December 2011, he intends to reach the summits of:

  • Aconcagua, Argentina, South America – 22,841ft/6,926 m
  • Everest, Nepal, Asia – 29,035 ft/8,850 m
  • Denali, Alaska, North America – 20,320 ft/6,194 m
  • Elbrus, Russia, Europe – 18,481 ft/5,633 m
  • Kilimanjaro, Tanzania, Africa – 19,340 ft/ 5,896 m
  • Carstensz Pyramid, Indonesia, Oceania – 16,023 ft/4,884 m

Arnette is also taking on the extended challenge of climbing an eighth mountain, Mt. Kosciuszko in Australia, which is part of the Oceania continent.

Cure Alzheimer's Fund on WGBH's Greater Boston

Cure Alzheimer's Fund co-founer, Jeff Morby and Research Consortium Chairman, Rudy Tanzi were featured on the tv show Greater Boston, November 8th on WGBH channel 2 in Boston. Emily Rooney interviewed the two about the founding of Cure Alzheimer's Fund and success in the search for an Alzheimer's Cure.

Watch the Greater Boston show>

Mindy Todd also interviewed Rudy Tanzi and Jeff Morby on a live radio interview aired on NPR's The Point.

Listen to the The Point: Alzheimer's interview>


NPR Features Cure Alzheimer's Fund

Cure Alzheimer's Fund was featured this morning in a two-part segment on National Public Radio. The piece details the founding of Cure Alzheimer's Fund, our venture approach  and some of the science that is providing the way to a cure. WGBH in Boston introduced the piece:

For more than five million patients and their estimated ten million caregivers, Alzheimer's disease is a scourge, a memory-stealing, brain-clogging affliction that costs the United States more than $170 billion a year, though its true impact on the lives of American families is incalculable.

In the first installment of our 2-part series, "Venture Philanthropy: An Investor's Approach to Curing Alzheimer's," reporter Sean Corcoran introduces us to a small group of local business leaders who are using their proven investment techniques — and their personal fortunes — to assemble what they believe are the world's most promising researchers to slow, stop or reverse the disease.

Listen to Venture Philanthropy Part One: A Business Approach to Curing Alzheimer's Disease>

Listen to Venture Philanthropy Part Two: Wanted a Man on the Moon Project to Cure Alzheimer's Disease>

Read the WGBH article Mass. Venture Capitalists Invest in Alzheimer's Research>

Support The 7 Summits Climb for Alzheimer's

The 7 Summits Climb for Alzheimer's: Memories are Everything is a year-long challenge by mountain climber and Alzheimer's disease advocate Alan Arnette to scale the 7 Summits, the highest peaks on each continent. Alan climbs in memory of his mother, who passed away in 2009 from Alzheimer's disease. Alzheimer's disease is the 6th leading cause of death in the United States, with another person newly diagnosed every 70 seconds. It is estimated to affect more than 5 million people in the United States and more than 25 million people worldwide. That's why Alan chose to climb the 7 Summits to raise awareness of the impact of this debilitating disease and $1 million to advance Alzheimers research as it is his hope that scientists can find a way to slow or stop Alzheimer's disease.

Wall Street Journal highlights McCance at TEDMED

Katherine Hobson features Cure Alzheimer's co-founder, Henry McCance and his TEDMED talk in the Wall Street Journal HealthBlog. She writes:

Henry McCance, chairman emeritus of venture-capital firm Greylock Partners, says the conventional way of funding academic research is ineffective. And he’s got an alternative strategy, based on how things work in the VC world. . .

McCance said, for every dollar spent on Alzheimer’s research, another $400 is spent on caregiving to those who suffer from the disease.

Researchers spend up to 30% of their time filling out grant applications, he said. The entire system encourages incremental research on already-established theories that moves the ball forward, at most, only a yard or two. With the Cure Alzheimer’s Fund, where McCance is a founding board member, there’s a different approach. Namely:

  • Proactively identify world-class researchers and fund them.
  • Relieve them from bureaucracy.
  • Network researchers in a virtual organization and insist they share data and results promptly and collaboratively.
  • Challenge your researchers to dare to be great.

Read the full story>


Curing Alzheimer's by 2020-TEDMED and Sandra Day O'Connor

Ending the disease by 2020 is a hot topic. The ambitious goal was the focus of Henry McCance and Rudy Tanzi's TEDMED talk yesterday and was a key point in Sandra Day O'Connor's excellent op-ed in the New York Times from earlier in the week. featured a summary of the Tanzi/McCance TEDMED talk:

Dr. Rudolph Tanzi of the Cure Alzheimer's Fund laid out an ambitious goal of finding a cure for the illness by the year 2020. Tanzi and venture capitalist Henry McCance, who helped found the fund in 2004, described the partnership that led to the identification of new genes that seem to play a role in Alzheimer’s disease, genes that are potential targets for new drug therapies.

Read more about TEDMED>

We highly recommend reading The Age of Alzheimer's by Sandra Day O'Connor, Stanley Prusiner and Ken Dychtwald published on Oct. 27, 2010. Just to give you a glimpse of the important message, here's how the piece starts:

OUR government is ignoring what is likely to become the single greatest threat to the health of Americans: Alzheimer’s disease, an illness that is 100 percent incurable and 100 percent fatal. It attacks rich and poor, white-collar and blue, and women and men, without regard to party. A degenerative disease, it steadily robs its victims of memory, judgment and dignity, leaves them unable to care for themselves and destroys their brain and their identity — often depleting their caregivers and families both emotionally and financially.

Starting on Jan. 1, our 79-million-strong baby boom generation will be turning 65 at the rate of one every eight seconds. That means more than 10,000 people per day, or more than four million per year, for the next 19 years facing an increased risk of Alzheimer’s.

Read the NYT Op-ed>