Find updates on the work of our researchers here, as well as news about recent advances in Alzheimer's science, funding and awareness.

Alzheimer’s Genes in the News: What does it all mean?

Setting the stage

The 10th Annual International Conference on Alzheimer’s Disease/Parkinson’s Disease (AD/PD) was held this March in Barcelona with thousands of researchers from 68 countries attending. Chief among the topics of interest was determining risk for the disease from genetics. The useful source for all things Alzheimer’s, The Alzheimer’s Research Forum (, provided extensive coverage on the conference.

Welcome Julie Ann Winton to the Cure Alzheimer’s Fund team!

Julie is joining Cure Alzheimer’s Fund as Development and Communications Associate to help provide content and direction to our communications program, support our fundraising efforts, help manage and expand our outreach programs and generally provide administrative support for Cure Alzheimer’s Fund and related researchers.

Deepak Chopra interviews CAF's Dr. Rudy Tanzi on this innovative Alzheimer's research

In this video Deepak Chopra talks to Dr. Rudy Tanzi about his groundbreaking research project, the Alzheimer's Genome Project, how gaining a better understanding of Alzheimer's disease leads to better treatments and a possible cure, and the important support of Cure Alzheimer's Fund in his research efforts.

Running to Support Research


Save the date – April 2, 2011! Join Running4Answers for the second annual 4-mile race and 2-mile fun run/fitness walk. The race will take place on the beautiful tree-lined, rolling hill streets of historic Roseland and Essex Fells, NJ. The race course is USATF-NJ sanctioned and certified and it is also part of the GRAND PRIX series. All proceeds go to support Cure Alzheimer’s Fund and research for a cure.

Alzheimer’s Genome Project Helps Progress for a Cure

Dr. Rudy Tanzi describes the role of Cure Alzheimer’s Fund and the Alzheimer’s Genome Project(link to AGP) in recent progress in Alzheimer’s disease research in a posting on He explains:

Prior to the Alzheimer’s Genome Project, we had discovered only four genes implicated in Alzheimer’s. And while these genes accounted for 30 percent of the inheritance of Alzheimer’s, we still had 70 percent of the genes left to discover.

CAF Applauds Recent Bipartisan Efforts by the Federal Government to Address Alzheimer’s Disease

Cure Alzheimer’s Fund applauds recent administration and congressional bipartisan action to help in the fight against Alzheimer’s.  Two recent events deserve acknowledgement and recognition.

National Family Caregivers Association Joins The 7 Summits Climb

Cure Alzheimer’s Fund together with Janssen Alzheimer Immunotherapy and Pfizer is pleased to announce the addition of the National Family Caregivers Association (NFCA) to The 7 Summits Climb for Alzheimer’s: Memories are Everything campaign.  NFCA joins just as alpine mountaineer and Alzheimer’s disease advocate Alan Arnette successfully summitted Aconcagua in Argentina, his second climb of the 7 Summits.  Congratulations Alan!

Two Down in The 7 Summits Climb for Alzheimer's

Please join us in congratulating Alan Arnette on his summit of Aconcogua, the second climb in his quest to reach the highest peak on each continent while raising awareness of Alzheimer's disease and funds to support research for a cure.

Alan was alo featured today in an impressive story in The Denver Post and is quoted:

Another Victim of Alzheimer's

We note with great sorrow the passing of Sargent Shriver.  Another victim of Alzheimer’s disease.

Shriver and his family have made tremendous contributions to American society through the Peace Corps, Special Olympics and so many other positive initiatives to affect the lives of people left out, left behind or disenfranchised in some way. His spirit and the determination of his wife Eunice infused this hardy and bold clan with creativity, energy and humor to challenge the most daunting of human conditions.

Maria Shriver and her brothers carry on this noble work, with Maria now paying special attention to the ravages of Alzheimer’s disease. From her wonderful children’s book, “What’s Happening to Grandpa” to her testimony on Capitol Hill for the need for more resources for Alzheimer’s care and research, Maria has become a true champion of the Alzheimer’s community .

We grieve for her, her family and the loss to America of one of its great and beneficent characters.

Read Sargent Shriver's Obituary>

Building Momentum Under the Radar

Breakthrough Research, Strong Fundraising, Mark Fifth Year of Cure Alzheimer’s Fund

Boston – A small nonprofit organization fully dedicated to Alzheimer’s research has quietly been making progress on an ambitious and aggressive research strategy for the development of effective therapies and discovery of an eventual cure for this devastating disease.

Taking a unique venture capital approach to philanthropy, Cure Alzheimer’s Fund (CAF) supports novel Alzheimer’s research that is aggressive, results-oriented, and ‘red-tape’-free. Bucking the recent downturn in charitable donations, the Fund raised a record $3.8 million in 2010 through individuals and federal and foundation grants, plowing all of it directly into research. CAF has raised $18.9 million since its inception at a time when the federal government budget for Alzheimer’s research and education has stagnated.

“Three families committed to wiping out Alzheimer’s decided five years ago that the ‘business-as-usual” model for Alzheimer’s research needed to be accelerated and founded Cure Alzheimer’s Fund,” said Tim Armour, President and CEO of the Fund. “Our network of supporters has grown because the only return the founders expect is a cure and we have made great strides to bring us closer to reaching that goal.”

This year alone CAF-supported research has made significant breakthroughs in better understanding the nature of Alzheimer’s, a key to finding a cure and more effective treatments.  Among that research is the confirmation of a link between Alzheimer’s and Type II diabetes, tied to a molecular mechanism in the gene SorCSI. The research, led by Dr. Sam Gandy, Professor in Alzheimer’s disease Research at the Mount Sinai School of Medicine, could open the door for more effective treatments for both diseases.

Dr. Gandy also developed a new approach for studying brain synapses that has yielded valuable information about the production of Amyloid-Beta oligomers (clumps of the Abeta peptide), which is known to play a key role in the onset of Alzheimer’s disease. Other research led by Dr. Rudy Tanzi, Harvard University Professor of Neurology and Director of Genetics and Aging Research, looked at the theory that Abeta is not entirely a “bad-guy” but in fact is part of the innate immune system.

Dr. Tanzi, who also serves as Chair of the CAF Research Consortium, heads up CAF’s cornerstone project, the Alzheimer’s Genome Project (AGP), which since 2005 has identified over 120 genes that contribute to risk for Alzheimer’s disease. TIME Magazine/CNN named the AGP as one of the top 10 medical breakthroughs of 2008.

“We look for scientists who are doing cutting-edge research and are willing to take a novel or even unconventional approach,” said Armour.

As science technology continues to advance, we believe we are on the cusp of a rare science moment, when intensive research could yield a real breakthrough for an Alzheimer’s cure,” Armour continued.  “With the first of the Baby Boomers turning 65 and experts predicting the number of people diagnosed with Alzheimer’s to skyrocket to 115 million in 2050, that moment can not come soon enough.”

About Cure Alzheimer's Fund

Cure Alzheimer's Fund™ is a 501c3 public charity whose mission is to fund research with the highest probability of slowing, stopping or reversing Alzheimer's disease. Cure Alzheimer’s Fund is characterized by a venture approach to philanthropy that targets funding to specific research objectives. The Fund’s founders underwrite all expenses and overhead, and all contributions go directly to research. The Foundation has no financial or intellectual property interest in the research funded, and will make known the results of all funded research as soon as possible. Cure Alzheimer’s Fund is a national organization with offices in Boston and Pittsburgh. For more information, visit