Find updates on the work of our researchers here, as well as news about recent advances in Alzheimer's science, funding and awareness.

Promising Study Suggests That a Drug for Immune Disorders May Offer Benefits to Alzheimer's Patients

A new study of an existing drug for immune disorders that may have positive effects for Alzheimer’s patients has attracted national attention lately. While phase III clinical trial results for Gammagard, an IVIG or “intravenous immunoglobulin therapy” by Baxter International are not expected until early 2013, hope for success must be balanced with a hard look at the data. The Wall Street Journal’s story on this drug and the prognosis for success by Dr.

Alzheimer Drug, Bapineuzumab, Fails Its First Clinical Trial

It was announced yesterday that Bapineuzumab, the Abeta immunotherapy drug, failed to meet cognitive and functional goals in a late stage trial of Alzheimer's patients who carry the APOE4 variant. “There was no reason to believe, unless there was a miracle, that this would be positive. It will only be the results of the non-APOE4 carriers that will inform us about the future [of bapineuzumab].”  said Rudolph Tanzi, Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School and MGH in Boston and Chair of the Cure Alzheimer’s Research Consortium.

Massachusetts General Hospital number 1 in the current issue of U.S. News and World Report’s “Best Hospital” survey.

Cure Alzheimer’s Fund is pleased to salute Massachusetts General Hospital for placing number 1 in the current issue of U.S. News and World Report’s “Best Hospital” survey. While Cure Alzheimer’s Fund has supported more than 24 leading Alzheimer’s research institutions since its inception in 2004, Mass General has received almost $10 million in research grants from Cure Alzheimer’s Fund during that time.

Gene Mutation Found that Protects Against Alzheimer’s, with Drug Discovery Implications

Genes are the specific DNA blueprints for life, and all genes play roles that are essential for health. But some can carry DNA variants that influence risk for disease, either by increasing or decreasing susceptibility. If a variation in a gene is very rare, it’s called a mutation. The mutation may cause disease, increase risk for a disease, protect against a disease, or have no impact on health at all.

New York Times Magazine focuses on Alzheimer’s Genetics

The New York Times Magazine appearing on Sunday, June 10, 2012, and available now online, carries a powerful narrative of a family’s journey through the tragedy of early-onset Alzheimer’s. It is a great contribution to Alzheimer’s awareness and the need for more research to end this disease, and a reinforcement of the priorities that the director of the National Institutes of Health has put on genetic research into the origins of Alzheimer’s.

Looking at Alzheimer's Through a Different Lens

Dr. Cathy Greenblat hasn’t always been a photographer, but she has always followed her heart. Before taking early retirement from Rutgers University, where she was a sociology professor for 35 years, she took a sabbatical in the spring of 2001 and made a decision that ultimately would change her life.

Untangling Tau: Seeking a Unified Understanding of Alzheimer's

Alzheimer’s research for many years has been dominated by a focus on Abeta “plaques,” a focus that largely has overlooked the other infamous hallmark of the disease—the tau-based neurofibrillary “tangles.” The research world recently has broadened its scope to include significant research into tau.

Climber Reaches the Halfway Point for Cure Alzheimer’s Fund

Bobby Zerwick left his comfortable home in Pennsylvania last March 10 with two goals: To hike the entire Appalachian Trail this summer and to raise much-needed research funds to find a cure for Alzheimer’s disease. The hike started at Springer Mountain in Georgia, and Bobby will hike north for a total of about five months. His journey will be completed this late summer or early fall when he reaches Mount Katahdin in Maine, having traveled more than 2,175 miles.

Rotary Club's Annual Conference in Bangkok, Thailand on May 9, 2012

THE COMING ALZHEIMER’S TSUNAMI: Society’s Next Big Challenge

Given the worldwide concern about Alzheimer’s disease, Mr. Kalyan Banerjee, president of Rotary International, invited Cure Alzheimer’s Fund to present at the Rotary Club’s Annual Conference in Bangkok, Thailand, on May 9, 2012.

Chronic Traumatic Brain Injuries Suffered by Veterans Similar to Those Experienced by Athletes

A new study, led by Cure Alzheimer’s Fund grant recipient Lee E. Goldstein, MD, Ph.D., of Boston University School of Medicine and co-authored by multiple researchers, including Cure Alzheimer's Fund Research Consortium chairman Rudy Tanzi, Ph.D., and Cure Alzheimer's Fund grant recipient Rob Moir, Ph.D., has found that war veterans who experience brain injuries from blast explosions are at risk for later developing neurological disease. This research was covered in multiple news outlets, including The New York Times.

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