Annual Report 2013

2013 Research Projects

Cure Alzheimer’s Fund is the only research organization with a real plan to end Alzheimer’s disease. Our unique funding strategy is 100 percent focused on finding a cure and supports the scientists doing the most innovative work to move knowledge of Alzheimer’s pathology most expeditiously to prevention and cure. Our ultimate objective is to stop the disease before it even starts.

By addressing the problem at the root and finding the major causes of the disease, we already are accelerating developments of effective therapies. The projects we fund are based on our roadmap, which we think is the quickest way to a cure.

Research Roadmap graphic

In 2013, Cure Alzheimer’s Fund distributed $4,576,000 for research supporting 14 projects.

Roadmap Intervention Point Project Researcher
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Whole Genome Sequencing
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Alzheimer’s Genome Project™
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The Amylin Protein of Diabetes Mellitus is an Antimicrobial Peptide
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Aβ Oligomers and the Pathogenic Spread of Tau Aggregation: Implications for Alzheimer’s Disease Mechanism and Treatment
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The Root of Alzheimer’s Disease: Purification and Characterization of Amyloid-beta Oligomers from the Human Brain
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BACE1 transcytosis in Alzheimer’s disease pathogenesis
Discovery of Alzheimer’s Disease Blood Biomarkers Using Phage Display Technology
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The roles of Eps homology domain (EHD) proteins and synaptic activity in axon transport of the Alzheimer’s β-secretase BACE1 in the brain
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Stem Cell Consortium
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Sleep and tauopathies: Effect of an anti-tau antibody
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Characterization of the pathological significance of a novel type of vascular amyloid
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Vascular Regenerative Therapy for Alzheimer’s Disease
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Normalizing Abeta synaptic depression with drugs targeting PICK1
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Effects of Inhibitors of Monoacylglycerol Lipase on Behavior and Synaptic Plasticity of Ts65Dn Mice, a Genetic Model of Down Syndrome
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Elucidation of the mechanism of action of Gamma Secretase Modulators